HIV PROTEASE INHIBITORS

Middlebury College

Winter Term Project

Grace Kim 98'

INTRODUCTION:This tutorial includes a general overview of the life cycle of the Human Immunodeficiency Virus (HIV) as well as information about the new drugs called protease inhibitors which fight HIV. HIV proteases are necessary for HIV to create new viruses that can infect other cells. Thus, inhibiting these proteases leads to a decrease in infectious HIV and an increase in CD4 cells. Although, protease inhibitors are not a cure for AIDS, the uses of these drugs in combination with nucleoside analogs greatly increases the rate of survival.

Table of Contents:

Human Immunodeficiency Virus (HIV) Life Cycle

HIV Protease

HIV Protease Inhibitor

Saquinavir

Conclusion

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