Lovastatin Molecules

Winter term project '97

This is lovastatin before it is hydrolyzed to its beta-hydroxyacid form. The ring group on the right is still attached.

This is lovastatin in a stick model. Notice the lactone ring on the right?

This is lovastatin in its beta-hydroxyacid form. After an oral dosage, water molecules will open the ring and form a terminal carboxylic acid group.